J Hand Surg Eur Vol. 2025 Mar 13:17531934251323855. doi: 10.1177/17531934251323855. Online ahead of print.ABSTRACTThis article explores the journey of developing a new implant for hand surgery, highlighting key stages from concept to market launch. It outlines the challenges posed by regulatory barr
J Tissue Eng. 2025 Mar 12;16:20417314251317542. doi: 10.1177/20417314251317542. eCollection 2025 Jan-Dec.ABSTRACTChronic wounds represent an unresolved medical challenge with significant impact for patients' quality of life and global healthcare. Diverse in origin, ischemic-hypoxic and inflammatory
J Hand Surg Eur Vol. 2025 Mar 12:17531934251324354. doi: 10.1177/17531934251324354. Online ahead of print.ABSTRACTIn this insightful and personal biographical article, Professor Bertelli recounts his journey from surgical problem to surgical solution with incredible detail. This was an invited artic
Brain. 2025 Mar 12:awaf103. doi: 10.1093/brain/awaf103. Online ahead of print.ABSTRACTParkinson's disease is characterized, in part, by hypoactivity of direct pathway inhibitory projections from striatum to the globus pallidus internus (GPi) and indirect pathway inhibitory projections from globus pa
J Am Acad Orthop Surg. 2025 Mar 11. doi: 10.5435/JAAOS-D-24-00817. Online ahead of print.ABSTRACTINTRODUCTION: We developed a custom digital drawing application to assess hand function. We conducted an initial validation study of this technique to (1) assess which drawing features are associated wit
Pol Merkur Lekarski. 2025;53(1):47-55. doi: 10.36740/Merkur202501107.ABSTRACTOBJECTIVE: Aim: The aim of the present study is to analyse and summarize the experience of the Department of Reconstructive and Plastic Microsurgery of the National Scientific Center of Surgery named after A.N. Syzganov in
J Nanobiotechnology. 2025 Mar 8;23(1):189. doi: 10.1186/s12951-025-03270-9.ABSTRACTPeriodontitis is a chronic inflammatory disease caused by plaque. In order to remove pathogens and promote tissue repair, the following steps need to be taken simultaneously: localizing the diseased area, improving th
BMC Womens Health. 2025 Mar 7;25(1):104. doi: 10.1186/s12905-025-03628-z.ABSTRACTBACKGROUND: This study aimed to evaluate the efficacy and safety of docetaxel plus capecitabine (TX) and docetaxel plus epirubicin (TE) in the treatment of human epidermal growth factor 2 (HER2)-negative breast cancer.M
BMC Anesthesiol. 2025 Mar 8;25(1):117. doi: 10.1186/s12871-025-02949-8.ABSTRACTBACKGROUND: Assessing heart rate variability (HRV) before a standardized surgery would help to explore further the relationship between the autonomic nervous system and pain.METHODS: A single-center prospective cohort of
Mol Cell Biochem. 2025 Mar 6. doi: 10.1007/s11010-025-05246-7. Online ahead of print.ABSTRACTMacrophages polarization play crucial roles in regulating inflammation and functional recovery after spinal cord injury (SCI). This study aimed to investigate the key macrophage polarization-related genes (M
J Wound Care. 2025 Mar 2;34(3):228-238. doi: 10.12968/jowc.2023.0037.ABSTRACTOBJECTIVE: There is a lack of studies on patient-reported outcomes of split-thickness skin graft (STSG) donor sites, especially on patient satisfaction. Donor site counselling could contribute to realistic patient expectati
J Surg Case Rep. 2025 Feb 28;2025(2):rjaf032. doi: 10.1093/jscr/rjaf032. eCollection 2025 Feb.ABSTRACTA 36-year-old female with recurrent giant cell tumor (GCT) of the left fifth metacarpal was treated with en bloc resection and free osteoarticular metatarsal graft from the fourth metatarsal. Donor
Annu Int Conf IEEE Eng Med Biol Soc. 2024 Jul;2024:1-6. doi: 10.1109/EMBC53108.2024.10781813.ABSTRACTIn this paper, we propose an innovative Graphical User Interface (GUI) aimed at improving preoperative planning and intra-operative guidance for precise spinal screw placement through vertebrae segme
Biomaterials. 2025 Aug;319:123210. doi: 10.1016/j.biomaterials.2025.123210. Epub 2025 Feb 24.ABSTRACTOsteoarthritis (OA) is a type of joint disease that influences millions of individuals. Regrettably, effective treatment for OA is currently unavailable. The challenge lies in the deep location of ch
IEEE Pulse. 2025 Jan-Feb;16(1):8-11. doi: 10.1109/MPULS.2025.3526482.ABSTRACTThe future of health care is poised for a transformative shift. Driven by the evolution of surgical robotics, artificial intelligence (AI), and an interconnected ecosystem, health practitioners will be empowered to make pro
Bioact Mater. 2025 Feb 13;47:502-512. doi: 10.1016/j.bioactmat.2025.01.037. eCollection 2025 May.ABSTRACTDuring interventional surgeries of implantable cardiovascular devices in addressing cardiovascular diseases (CVD), the inevitable tissue damage will trigger host inflammation and vascular lumen i
BMC Med Educ. 2025 Feb 28;25(1):325. doi: 10.1186/s12909-025-06863-y.ABSTRACTBACKGROUND: Trauma surgery is characterized by high-acuity, low-frequency events. While trauma remains a leading cause of death and disability worldwide, surgical residents experience reduced trauma operative volumes during
J Clin Med. 2025 Feb 8;14(4):1092. doi: 10.3390/jcm14041092.ABSTRACTBackground: The aim of this biomechanical investigation was to evaluate a V-shaped three-point graft tenodesis technique using a free palmaris longus (PL) tendon for reconstructing traumatic A2 pulley lesions and to compare its biom
Life (Basel). 2025 Jan 22;15(2):146. doi: 10.3390/life15020146.ABSTRACTPressure ulcers are a persistent and growing challenge in modern medicine, with prevalence rates ranging from 3.4% to 32.4% globally. Demographic changes suggest an increasing number of patients at risk, emphasizing the need for
Children (Basel). 2025 Jan 24;12(2):130. doi: 10.3390/children12020130.ABSTRACTBackground: The Child Amputee Prosthetics Project-Prosthesis Satisfaction Inventory (CAPP-PSI) is a comprehensive instrument designed to measure satisfaction across functionality, aesthetic, and service domains. This stud
Korean J Radiol. 2025 Mar;26(3):230-238. doi: 10.3348/kjr.2024.0883.ABSTRACTOBJECTIVE: To assess the effect of transarterial embolization (TAE) for adhesive capsulitis (AC) by evaluating clinical outcomes and changes in inflammation using magnetic resonance imaging (MRI).MATERIALS AND METHODS: Patie
J Funct Biomater. 2025 Feb 7;16(2):51. doi: 10.3390/jfb16020051.ABSTRACTFibrosis after full-thickness wound healing-especially after severe burn wounds-remains a clinically relevant problem. Biomaterials that mimic the lost dermal extracellular matrix have shown promise but cannot completely prevent
Tech Hand Up Extrem Surg. 2025 Feb 25. doi: 10.1097/BTH.0000000000000506. Online ahead of print.ABSTRACTVascularized osteochondral flap reconstruction is an innovation with several potential benefits, but there are limited described autologous donor site options. This study explores the distal clavi
J Cachexia Sarcopenia Muscle. 2025 Feb;16(1):e13732. doi: 10.1002/jcsm.13732.ABSTRACTBACKGROUND: Cancer cachexia presents a significant challenge, but the ghrelin agonist anamorelin shows promise as a potential treatment. This study examined whether the baseline systemic inflammatory response (SIR)
